BDBM50137995 3-O-Cyclobutylmethyl-10-keto-N-cyclobutylmethylmorphinan::CHEMBL298446

SMILES: O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(OCC3CCC3)ccc12

InChI Key: InChIKey=CNPKHMRIMIVLGC-LLZJGCNPSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50137995 (3-O-Cyclobutylmethyl-10-keto-N-cyclobutylmethylmor...) Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(OCC3CCC3)ccc12 Show InChI InChI=1S/C26H35NO2/c28-25-21-11-10-20(29-17-19-7-4-8-19)15-23(21)26-12-2-1-9-22(26)24(25)27(14-13-26)16-18-5-3-6-18/h10-11,15,18-19,22,24H,1-9,12-14,16-17H2/t22-,24-,26+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50137995 (3-O-Cyclobutylmethyl-10-keto-N-cyclobutylmethylmor...) Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(OCC3CCC3)ccc12 Show InChI InChI=1S/C26H35NO2/c28-25-21-11-10-20(29-17-19-7-4-8-19)15-23(21)26-12-2-1-9-22(26)24(25)27(14-13-26)16-18-5-3-6-18/h10-11,15,18-19,22,24H,1-9,12-14,16-17H2/t22-,24-,26+/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50137995 (3-O-Cyclobutylmethyl-10-keto-N-cyclobutylmethylmor...) Show SMILES O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(OCC3CCC3)ccc12 Show InChI InChI=1S/C26H35NO2/c28-25-21-11-10-20(29-17-19-7-4-8-19)15-23(21)26-12-2-1-9-22(26)24(25)27(14-13-26)16-18-5-3-6-18/h10-11,15,18-19,22,24H,1-9,12-14,16-17H2/t22-,24-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.				J Med Chem 47: 165-74 (2003) Article DOI: 10.1021/jm0304156 BindingDB Entry DOI: 10.7270/Q2KD1XB2
					More data for this Ligand-Target Pair