BDBM50138292 (S)-2-(4-Chloro-benzyl)-1-{4-[2-(2-cyclopropyl-1-methanesulfonyl-ethyl)-phenyl]-piperazin-1-yl}-4-(4-propyl-piperazin-1-yl)-butane-1,4-dione::CHEMBL338766

SMILES: CCCN1CCN(CC1)C(=O)C[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1N(CC1CC1)S(C)(=O)=O

InChI Key: InChIKey=XYLTVWHSEAYDPG-NDEPHWFRSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50138292 ((S)-2-(4-Chloro-benzyl)-1-{4-[2-(2-cyclopropyl-1-m...) Show SMILES CCCN1CCN(CC1)C(=O)C[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1N(CC1CC1)S(C)(=O)=O Show InChI InChI=1S/C33H46ClN5O4S/c1-3-14-35-15-17-37(18-16-35)32(40)24-28(23-26-10-12-29(34)13-11-26)33(41)38-21-19-36(20-22-38)30-6-4-5-7-31(30)39(44(2,42)43)25-27-8-9-27/h4-7,10-13,27-28H,3,8-9,14-25H2,1-2H3/t28-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human melanocortin 3 receptor				Bioorg Med Chem Lett 14: 377-81 (2003) BindingDB Entry DOI: 10.7270/Q2902363
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50138292 ((S)-2-(4-Chloro-benzyl)-1-{4-[2-(2-cyclopropyl-1-m...) Show SMILES CCCN1CCN(CC1)C(=O)C[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1N(CC1CC1)S(C)(=O)=O Show InChI InChI=1S/C33H46ClN5O4S/c1-3-14-35-15-17-37(18-16-35)32(40)24-28(23-26-10-12-29(34)13-11-26)33(41)38-21-19-36(20-22-38)30-6-4-5-7-31(30)39(44(2,42)43)25-27-8-9-27/h4-7,10-13,27-28H,3,8-9,14-25H2,1-2H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Intracellular level of cAMP in cells expressing the melanocortin 4 receptor				Bioorg Med Chem Lett 14: 377-81 (2003) BindingDB Entry DOI: 10.7270/Q2902363
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50138292 ((S)-2-(4-Chloro-benzyl)-1-{4-[2-(2-cyclopropyl-1-m...) Show SMILES CCCN1CCN(CC1)C(=O)C[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1N(CC1CC1)S(C)(=O)=O Show InChI InChI=1S/C33H46ClN5O4S/c1-3-14-35-15-17-37(18-16-35)32(40)24-28(23-26-10-12-29(34)13-11-26)33(41)38-21-19-36(20-22-38)30-6-4-5-7-31(30)39(44(2,42)43)25-27-8-9-27/h4-7,10-13,27-28H,3,8-9,14-25H2,1-2H3/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity against [125I]-NDP-alpha-MSH binding to the human melanocortin 4 receptor				Bioorg Med Chem Lett 14: 377-81 (2003) BindingDB Entry DOI: 10.7270/Q2902363
					More data for this Ligand-Target Pair
Melanocortin receptor 1 (Mus musculus)	BDBM50138292 ((S)-2-(4-Chloro-benzyl)-1-{4-[2-(2-cyclopropyl-1-m...) Show SMILES CCCN1CCN(CC1)C(=O)C[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1N(CC1CC1)S(C)(=O)=O Show InChI InChI=1S/C33H46ClN5O4S/c1-3-14-35-15-17-37(18-16-35)32(40)24-28(23-26-10-12-29(34)13-11-26)33(41)38-21-19-36(20-22-38)30-6-4-5-7-31(30)39(44(2,42)43)25-27-8-9-27/h4-7,10-13,27-28H,3,8-9,14-25H2,1-2H3/t28-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory activity against mouse melanocortin 1 receptor				Bioorg Med Chem Lett 14: 377-81 (2003) BindingDB Entry DOI: 10.7270/Q2902363
					More data for this Ligand-Target Pair