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SMILES: Oc1ccc2CCCN(Cc3ccccc3C(=O)NCC\C=C\c3ccccc3)Cc2c1

InChI Key: InChIKey=FFBZLGCQGBBDDO-IZZDOVSWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138593   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent glycine transporter 2


(Homo sapiens (Human))		BDBM50138593
PNG
(2-(8-Hydroxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-y...)
Show SMILES Oc1ccc2CCCN(Cc3ccccc3C(=O)NCC\C=C\c3ccccc3)Cc2c1
Show InChI InChI=1S/C28H30N2O2/c31-26-16-15-23-13-8-18-30(21-25(23)19-26)20-24-12-4-5-14-27(24)28(32)29-17-7-6-11-22-9-2-1-3-10-22/h1-6,9-12,14-16,19,31H,7-8,13,17-18,20-21H2,(H,29,32)/b11-6+
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PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



Pharmacopeia, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell line

Bioorg Med Chem Lett 14: 545-8 (2003)


BindingDB Entry DOI: 10.7270/Q2M9083Z
More data for this
Ligand-Target Pair