BDBM50138604 CHEMBL153159::N-Benzyl-2-{4-[(R)-2-hydroxy-3-(2-methyl-benzothiazol-5-yloxy)-propyl]-piperazin-1-yl}-acetamide

SMILES: Cc1nc2cc(OC[C@H](O)CN3CCN(CC(=O)NCc4ccccc4)CC3)ccc2s1

InChI Key: InChIKey=LOIOXQGQSFDTMG-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Palmitoyl-CoA oxidase (Rattus norvegicus)	BDBM50138604 (CHEMBL153159 | N-Benzyl-2-{4-[(R)-2-hydroxy-3-(2-m...) Show SMILES Cc1nc2cc(OC[C@H](O)CN3CCN(CC(=O)NCc4ccccc4)CC3)ccc2s1 Show InChI InChI=1S/C24H30N4O3S/c1-18-26-22-13-21(7-8-23(22)32-18)31-17-20(29)15-27-9-11-28(12-10-27)16-24(30)25-14-19-5-3-2-4-6-19/h2-8,13,20,29H,9-12,14-17H2,1H3,(H,25,30)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
CV Therapeutics Curated by ChEMBL					Assay Description Inhibitory activity against Palmitoyl-CoA oxidase to inhibit rat heart mitochondrial Palmitoyl-CoA oxidation.				Bioorg Med Chem Lett 14: 549-52 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HD4
					More data for this Ligand-Target Pair