Found 3 hits for monomerid = 50138835 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50138835
(CHEMBL3752269)Show SMILES CCCCCCCCNC(=O)[C@H](Cc1ccc(OCc2cccc(c2)[N+]([O-])=O)cc1)NC(=O)[C@H]1CC[C@H](CN)CC1 |r,wU:36.38,wD:33.34,11.11,(17.08,-3.75,;16.01,-3.13,;14.67,-3.89,;13.34,-3.12,;12,-3.88,;10.67,-3.11,;9.34,-3.88,;8,-3.1,;6.67,-3.87,;5.33,-3.09,;5.34,-1.86,;4,-3.86,;3.99,-5.4,;5.33,-6.17,;5.33,-7.71,;6.66,-8.48,;8,-7.71,;9.33,-8.48,;10.66,-7.71,;12,-8.47,;12,-10.01,;13.33,-10.78,;14.67,-10.01,;14.67,-8.47,;13.33,-7.7,;16,-7.71,;16.01,-6.48,;17.07,-8.32,;8,-6.17,;6.66,-5.4,;2.66,-3.08,;2.67,-1.54,;3.73,-.93,;1.33,-.77,;1.33,.77,;,1.54,;-1.33,.77,;-2.67,1.54,;-2.66,2.78,;-1.33,-.77,;,-1.54,)| Show InChI InChI=1S/C32H46N4O5/c1-2-3-4-5-6-7-19-34-32(38)30(35-31(37)27-15-11-25(22-33)12-16-27)21-24-13-17-29(18-14-24)41-23-26-9-8-10-28(20-26)36(39)40/h8-10,13-14,17-18,20,25,27,30H,2-7,11-12,15-16,19,21-23,33H2,1H3,(H,34,38)(H,35,37)/t25-,27-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Inhibition of urokinase (unknown origin) using Pyr-Glu-Gly-Arg-pNA as substrate |
Bioorg Med Chem 24: 545-53 (2016)
BindingDB Entry DOI: 10.7270/Q29888VQ |
More data for this
Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM50138835
(CHEMBL3752269)Show SMILES CCCCCCCCNC(=O)[C@H](Cc1ccc(OCc2cccc(c2)[N+]([O-])=O)cc1)NC(=O)[C@H]1CC[C@H](CN)CC1 |r,wU:36.38,wD:33.34,11.11,(17.08,-3.75,;16.01,-3.13,;14.67,-3.89,;13.34,-3.12,;12,-3.88,;10.67,-3.11,;9.34,-3.88,;8,-3.1,;6.67,-3.87,;5.33,-3.09,;5.34,-1.86,;4,-3.86,;3.99,-5.4,;5.33,-6.17,;5.33,-7.71,;6.66,-8.48,;8,-7.71,;9.33,-8.48,;10.66,-7.71,;12,-8.47,;12,-10.01,;13.33,-10.78,;14.67,-10.01,;14.67,-8.47,;13.33,-7.7,;16,-7.71,;16.01,-6.48,;17.07,-8.32,;8,-6.17,;6.66,-5.4,;2.66,-3.08,;2.67,-1.54,;3.73,-.93,;1.33,-.77,;1.33,.77,;,1.54,;-1.33,.77,;-2.67,1.54,;-2.66,2.78,;-1.33,-.77,;,-1.54,)| Show InChI InChI=1S/C32H46N4O5/c1-2-3-4-5-6-7-19-34-32(38)30(35-31(37)27-15-11-25(22-33)12-16-27)21-24-13-17-29(18-14-24)41-23-26-9-8-10-28(20-26)36(39)40/h8-10,13-14,17-18,20,25,27,30H,2-7,11-12,15-16,19,21-23,33H2,1H3,(H,34,38)(H,35,37)/t25-,27-,30-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Inhibition of plasmin (unknown origin) using H-D-Val-Leu-Lys-pNA as substrate |
Bioorg Med Chem 24: 545-53 (2016)
BindingDB Entry DOI: 10.7270/Q29888VQ |
More data for this
Ligand-Target Pair | |
Trypsin
(Homo sapiens (Human)) | BDBM50138835
(CHEMBL3752269)Show SMILES CCCCCCCCNC(=O)[C@H](Cc1ccc(OCc2cccc(c2)[N+]([O-])=O)cc1)NC(=O)[C@H]1CC[C@H](CN)CC1 |r,wU:36.38,wD:33.34,11.11,(17.08,-3.75,;16.01,-3.13,;14.67,-3.89,;13.34,-3.12,;12,-3.88,;10.67,-3.11,;9.34,-3.88,;8,-3.1,;6.67,-3.87,;5.33,-3.09,;5.34,-1.86,;4,-3.86,;3.99,-5.4,;5.33,-6.17,;5.33,-7.71,;6.66,-8.48,;8,-7.71,;9.33,-8.48,;10.66,-7.71,;12,-8.47,;12,-10.01,;13.33,-10.78,;14.67,-10.01,;14.67,-8.47,;13.33,-7.7,;16,-7.71,;16.01,-6.48,;17.07,-8.32,;8,-6.17,;6.66,-5.4,;2.66,-3.08,;2.67,-1.54,;3.73,-.93,;1.33,-.77,;1.33,.77,;,1.54,;-1.33,.77,;-2.67,1.54,;-2.66,2.78,;-1.33,-.77,;,-1.54,)| Show InChI InChI=1S/C32H46N4O5/c1-2-3-4-5-6-7-19-34-32(38)30(35-31(37)27-15-11-25(22-33)12-16-27)21-24-13-17-29(18-14-24)41-23-26-9-8-10-28(20-26)36(39)40/h8-10,13-14,17-18,20,25,27,30H,2-7,11-12,15-16,19,21-23,33H2,1H3,(H,34,38)(H,35,37)/t25-,27-,30-/m0/s1 | PDB
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kobe Gakuin University
Curated by ChEMBL
| Assay Description
Inhibition of trypsin (unknown origin) using H-D-Phe-Pip-Arg-pNA as substrate |
Bioorg Med Chem 24: 545-53 (2016)
BindingDB Entry DOI: 10.7270/Q29888VQ |
More data for this
Ligand-Target Pair | |
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