BDBM50140156 CHEMBL2387062

SMILES: COc1ccccc1\C=C\c1ccccc1

InChI Key: InChIKey=FLQOKJWUYDGZIT-VAWYXSNFSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50140156 (CHEMBL2387062) Show SMILES COc1ccccc1\C=C\c1ccccc1 Show InChI InChI=1S/C15H14O/c1-16-15-10-6-5-9-14(15)12-11-13-7-3-2-4-8-13/h2-12H,1H3/b12-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase of intracellular calcium level				Bioorg Med Chem Lett 26: 899-902 (2016) BindingDB Entry DOI: 10.7270/Q2765H6N
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50140156 (CHEMBL2387062) Show SMILES COc1ccccc1\C=C\c1ccccc1 Show InChI InChI=1S/C15H14O/c1-16-15-10-6-5-9-14(15)12-11-13-7-3-2-4-8-13/h2-12H,1H3/b12-11+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	880	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 26: 899-902 (2016) BindingDB Entry DOI: 10.7270/Q2765H6N
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50140156 (CHEMBL2387062) Show SMILES COc1ccccc1\C=C\c1ccccc1 Show InChI InChI=1S/C15H14O/c1-16-15-10-6-5-9-14(15)12-11-13-7-3-2-4-8-13/h2-12H,1H3/b12-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hyogo University of Health Sciences Curated by ChEMBL					Assay Description Inhibition of TRPA1 (unknown origin)				Bioorg Med Chem Lett 27: 3167-3172 (2017) Article DOI: 10.1016/j.bmcl.2017.05.025 BindingDB Entry DOI: 10.7270/Q2TH8Q4R
					More data for this Ligand-Target Pair
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50140156 (CHEMBL2387062) Show SMILES COc1ccccc1\C=C\c1ccccc1 Show InChI InChI=1S/C15H14O/c1-16-15-10-6-5-9-14(15)12-11-13-7-3-2-4-8-13/h2-12H,1H3/b12-11+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a
University of New Mexico Curated by ChEMBL					Assay Description Activation of Nrf2 (unknown origin) expressed in human HepG2 cells after 5 hrs by ARE-driven luciferase reporter gene assay				Bioorg Med Chem 25: 1423-1430 (2017) Article DOI: 10.1016/j.bmc.2017.01.005 BindingDB Entry DOI: 10.7270/Q23T9KDN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50140156 (CHEMBL2387062) Show SMILES COc1ccccc1\C=C\c1ccccc1 Show InChI InChI=1S/C15H14O/c1-16-15-10-6-5-9-14(15)12-11-13-7-3-2-4-8-13/h2-12H,1H3/b12-11+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 26: 899-902 (2016) BindingDB Entry DOI: 10.7270/Q2765H6N
					More data for this Ligand-Target Pair