BDBM50140175 CHEMBL3753729

SMILES: C[C@@H](NCc1cc2c(cccc2[nH]1)-c1ccccc1)c1cccc2ccccc12

InChI Key: InChIKey=YJVKPJQXYZUEDY-LJQANCHMSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium sensing receptor (Rattus norvegicus)	BDBM50140175 (CHEMBL3753729) Show SMILES C[C@@H](NCc1cc2c(cccc2[nH]1)-c1ccccc1)c1cccc2ccccc12 |r| Show InChI InChI=1S/C27H24N2/c1-19(23-14-7-12-21-11-5-6-13-24(21)23)28-18-22-17-26-25(15-8-16-27(26)29-22)20-9-3-2-4-10-20/h2-17,19,28-29H,18H2,1H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	136	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) BindingDB Entry DOI: 10.7270/Q2TX3H7V
					More data for this Ligand-Target Pair
Calcium sensing receptor (Rattus norvegicus)	BDBM50140175 (CHEMBL3753729) Show SMILES C[C@@H](NCc1cc2c(cccc2[nH]1)-c1ccccc1)c1cccc2ccccc12 |r| Show InChI InChI=1S/C27H24N2/c1-19(23-14-7-12-21-11-5-6-13-24(21)23)28-18-22-17-26-25(15-8-16-27(26)29-22)20-9-3-2-4-10-20/h2-17,19,28-29H,18H2,1H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	135	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Agonist activity at rat brain CaSR expressed in CHO cells assessed as inositol phosphate production in presence of 3 mM extracellular Ca2+ by IP-one ...				Bioorg Med Chem 24: 554-69 (2016) BindingDB Entry DOI: 10.7270/Q2TX3H7V
					More data for this Ligand-Target Pair