BDBM50140569 CHEMBL3752995
SMILES: COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-c1nccs1
InChI Key: InChIKey=CGTZEGZYMMNVOO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Lysine-specific demethylase 6B (Homo sapiens (Human)) | BDBM50140569 (CHEMBL3752995) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay | Bioorg Med Chem Lett 26: 721-5 (2016) BindingDB Entry DOI: 10.7270/Q2P55QC2 | |||||||||||
More data for this Ligand-Target Pair |