BindingDB logo
myBDB logout

BDBM50141052 3-[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-5-isobutyl-thiophene-2-sulfonic acid diphenylacetyl-amide::CHEMBL415875

SMILES: CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1cc(CC(C)C)sc1S(=O)(=O)NC(=O)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=YFGFVMIVJMMSMA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141052   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))		BDBM50141052
PNG
(3-[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3...)
Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1cc(CC(C)C)sc1S(=O)(=O)NC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C39H40N4O3S2/c1-6-34-41-36-26(4)22-27(5)40-37(36)43(34)24-28-17-19-29(20-18-28)33-23-32(21-25(2)3)47-39(33)48(45,46)42-38(44)35(30-13-9-7-10-14-30)31-15-11-8-12-16-31/h7-20,22-23,25,35H,6,21,24H2,1-5H3,(H,42,44)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity at Angiotensin II receptor, type 2 in pig uterus myometrial membranes by [125I]-Ang II displacement.

J Med Chem 47: 1536-46 (2004)


Article DOI: 10.1021/jm031031i
BindingDB Entry DOI: 10.7270/Q2NS0TBV
More data for this
Ligand-Target Pair