BDBM50141068 CHEMBL3754525
SMILES: [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C=C(CC[C@]12C)c1nnn[nH]1
InChI Key: InChIKey=HVXDOJKJRIHIDP-UKSSEWCLSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50141068 (CHEMBL3754525) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
University Institute of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Inhibition of human 5alpha-2 reductase expressed in HEK293 cells assessed as suppression of conversion of [3]androstenedione incubated for 30 mins by... | Bioorg Med Chem 24: 779-88 (2016) BindingDB Entry DOI: 10.7270/Q21G0P3C | |||||||||||
More data for this Ligand-Target Pair |