BDBM50141103 CHEMBL3760082

SMILES: COc1ccc(C=O)cc1-c1cc2c(N[C@H](C)c3ccccc3)ncnc2s1

InChI Key: InChIKey=CKCCUWSFMHCHHH-CQSZACIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50141103 (CHEMBL3760082) Show SMILES COc1ccc(C=O)cc1-c1cc2c(N[C@H](C)c3ccccc3)ncnc2s1 |r| Show InChI InChI=1S/C22H19N3O2S/c1-14(16-6-4-3-5-7-16)25-21-18-11-20(28-22(18)24-13-23-21)17-10-15(12-26)8-9-19(17)27-2/h3-14H,1-2H3,(H,23,24,25)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Norwegian University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) by Z -LYTE assay				Eur J Med Chem 107: 255-74 (2015) BindingDB Entry DOI: 10.7270/Q2C24Z8D
					More data for this Ligand-Target Pair