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SMILES: CN(C)CCOc1cc2c(Nc3cccc(Br)c3)c(cnc2cn1)C#N

InChI Key: InChIKey=JOJWRSKVHPYAGI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50141152 (4-(3-Bromo-phenylamino)-6-(2-dimethylamino-ethoxy)...) Show SMILES CN(C)CCOc1cc2c(Nc3cccc(Br)c3)c(cnc2cn1)C#N Show InChI InChI=1S/C19H18BrN5O/c1-25(2)6-7-26-18-9-16-17(12-23-18)22-11-13(10-21)19(16)24-15-5-3-4-14(20)8-15/h3-5,8-9,11-12H,6-7H2,1-2H3,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of epidermal growth factor receptor kinase autophosphorylation				Bioorg Med Chem Lett 14: 1411-6 (2004) Article DOI: 10.1016/j.bmcl.2004.01.034 BindingDB Entry DOI: 10.7270/Q2G161DC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50141152 (4-(3-Bromo-phenylamino)-6-(2-dimethylamino-ethoxy)...) Show SMILES CN(C)CCOc1cc2c(Nc3cccc(Br)c3)c(cnc2cn1)C#N Show InChI InChI=1S/C19H18BrN5O/c1-25(2)6-7-26-18-9-16-17(12-23-18)22-11-13(10-21)19(16)24-15-5-3-4-14(20)8-15/h3-5,8-9,11-12H,6-7H2,1-2H3,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of epidermal growth factor receptor kinase autophosphorylation				Bioorg Med Chem Lett 14: 1411-6 (2004) Article DOI: 10.1016/j.bmcl.2004.01.034 BindingDB Entry DOI: 10.7270/Q2G161DC
					More data for this Ligand-Target Pair