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SMILES: Nc1ccccc1SC(=N)C(C#N)c1cccc(c1)C(O)c1ccco1

InChI Key: InChIKey=RHDRPKBXKKAZNW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141414   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual specificity mitogen-activated protein kinase kinase 1


(Homo sapiens (Human))		BDBM50141414
PNG
((Z)-3-Amino-3-(2-amino-phenylsulfanyl)-2-[3-(furan...)
Show SMILES Nc1ccccc1SC(=N)C(C#N)c1cccc(c1)C(O)c1ccco1
Show InChI InChI=1S/C20H17N3O2S/c21-12-15(20(23)26-18-9-2-1-7-16(18)22)13-5-3-6-14(11-13)19(24)17-8-4-10-25-17/h1-11,15,19,23-24H,22H2
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n/an/a 323n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL


Assay Description
Inhibitory potency against mitogen activated protein kinase kinase kinase 1

Bioorg Med Chem Lett 14: 1483-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.012
BindingDB Entry DOI: 10.7270/Q2H131F0
More data for this
Ligand-Target Pair