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SMILES: Cc1cccc(c1)C(O)c1cccc(c1)C(C#N)C(=N)Sc1ccc(N)cc1

InChI Key: InChIKey=RLKJVJFXZAQCSK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141420   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual specificity mitogen-activated protein kinase kinase 1


(Homo sapiens (Human))		BDBM50141420
PNG
((Z)-3-Amino-3-(4-amino-phenylsulfanyl)-2-[3-(hydro...)
Show SMILES Cc1cccc(c1)C(O)c1cccc(c1)C(C#N)C(=N)Sc1ccc(N)cc1
Show InChI InChI=1S/C23H21N3OS/c1-15-4-2-6-17(12-15)22(27)18-7-3-5-16(13-18)21(14-24)23(26)28-20-10-8-19(25)9-11-20/h2-13,21-22,26-27H,25H2,1H3
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n/an/a 503n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceuticals Research Institute

Curated by ChEMBL


Assay Description
Inhibitory potency against mitogen activated protein kinase kinase kinase 1

Bioorg Med Chem Lett 14: 1483-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.012
BindingDB Entry DOI: 10.7270/Q2H131F0
More data for this
Ligand-Target Pair