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SMILES: COc1ccc(cc1OC)[C@H](C)NC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1

InChI Key: InChIKey=MWQNNORZVYFWQB-IBGZPJMESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142060   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50142060
PNG
(1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...)
Show SMILES COc1ccc(cc1OC)[C@H](C)NC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccn1
Show InChI InChI=1S/C29H32N4O3/c1-19(20-13-15-26(35-2)27(18-20)36-3)31-29(34)21-12-14-25-24(17-21)32-28(23-11-7-8-16-30-23)33(25)22-9-5-4-6-10-22/h7-8,11-19,22H,4-6,9-10H2,1-3H3,(H,31,34)/t19-/m0/s1
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.

Bioorg Med Chem Lett 14: 967-71 (2004)


Article DOI: 10.1016/j.bmcl.2003.12.032
BindingDB Entry DOI: 10.7270/Q29C6WVF
More data for this
Ligand-Target Pair