BDBM50142453 1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::1-{3-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-yl]-propyl}-3-[3-(1-methyl-1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL43423

SMILES: Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1

InChI Key: InChIKey=DQSLLQXQXYFIRA-IBGZPJMESA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50142453 (1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...) Show SMILES Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 Show InChI InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-6-2-7-22(16-20)27-24(33)26-12-4-14-32-13-3-5-19(17-32)15-18-8-10-21(25)11-9-18/h2,6-11,16,19H,3-5,12-15,17H2,1H3,(H2,26,27,33)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against C-C chemokine receptor type 3 using human [125I]-eotaxin.				Bioorg Med Chem Lett 14: 1645-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.059 BindingDB Entry DOI: 10.7270/Q2RB741N
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50142453 (1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...) Show SMILES Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 Show InChI InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-6-2-7-22(16-20)27-24(33)26-12-4-14-32-13-3-5-19(17-32)15-18-8-10-21(25)11-9-18/h2,6-11,16,19H,3-5,12-15,17H2,1H3,(H2,26,27,33)/t19-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50142453 (1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...) Show SMILES Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 Show InChI InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-6-2-7-22(16-20)27-24(33)26-12-4-14-32-13-3-5-19(17-32)15-18-8-10-21(25)11-9-18/h2,6-11,16,19H,3-5,12-15,17H2,1H3,(H2,26,27,33)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 receptor in human eosinophil assessed as inhibition of eotaxin-induced chemotaxis				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50142453 (1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...) Show SMILES Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1 Show InChI InChI=1S/C24H30FN7O/c1-31-23(28-29-30-31)20-6-2-7-22(16-20)27-24(33)26-12-4-14-32-13-3-5-19(17-32)15-18-8-10-21(25)11-9-18/h2,6-11,16,19H,3-5,12-15,17H2,1H3,(H2,26,27,33)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair