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SMILES: OC(CCN1C(=O)CC2(CCCC2)CC1=O)CN1CCN(CC1)c1cnccn1

InChI Key: InChIKey=DPPAPOFAVBDXOJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142646   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50142646
PNG
(8-[3-Hydroxy-4-(2,3,5,6-tetrahydro-[1,2']bipyrazin...)
Show SMILES OC(CCN1C(=O)CC2(CCCC2)CC1=O)CN1CCN(CC1)c1cnccn1
Show InChI InChI=1S/C21H31N5O3/c27-17(16-24-9-11-25(12-10-24)18-15-22-6-7-23-18)3-8-26-19(28)13-21(14-20(26)29)4-1-2-5-21/h6-7,15,17,27H,1-5,8-14,16H2
PDB

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antibodypedia
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PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



ArQule Inc

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT in human CYP3A4 assay

Bioorg Med Chem Lett 14: 1709-12 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.045
BindingDB Entry DOI: 10.7270/Q2ZW1KB5
More data for this
Ligand-Target Pair