BDBM50143864 5-[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]dec-8-yl]-2-(3,5-dimethyl-isoxazole-4-sulfonylamino)-5-oxo-pentanoic acid::CHEMBL418481

SMILES: Cc1noc(C)c1S(=O)(=O)N[C@@H](CCC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2)C(N)=N)CC1)C(O)=O

InChI Key: InChIKey=DYYSGNJUTBUSGU-IBGZPJMESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50143864 (5-[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spir...) Show SMILES Cc1noc(C)c1S(=O)(=O)N[C@@H](CCC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2)C(N)=N)CC1)C(O)=O Show InChI InChI=1S/C25H32N6O7S/c1-15-21(16(2)38-28-15)39(36,37)29-19(23(33)34)7-8-20(32)30-12-9-25(10-13-30)11-14-31(24(25)35)18-5-3-17(4-6-18)22(26)27/h3-6,19,29H,7-14H2,1-2H3,(H3,26,27)(H,33,34)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP)				J Med Chem 47: 2037-61 (2004) Article DOI: 10.1021/jm030354b BindingDB Entry DOI: 10.7270/Q2FQ9W1H
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50143864 (5-[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spir...) Show SMILES Cc1noc(C)c1S(=O)(=O)N[C@@H](CCC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2)C(N)=N)CC1)C(O)=O Show InChI InChI=1S/C25H32N6O7S/c1-15-21(16(2)38-28-15)39(36,37)29-19(23(33)34)7-8-20(32)30-12-9-25(10-13-30)11-14-31(24(25)35)18-5-3-17(4-6-18)22(26)27/h3-6,19,29H,7-14H2,1-2H3,(H3,26,27)(H,33,34)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)				J Med Chem 47: 2037-61 (2004) Article DOI: 10.1021/jm030354b BindingDB Entry DOI: 10.7270/Q2FQ9W1H
					More data for this Ligand-Target Pair