BDBM50143995 CHEMBL3758261

SMILES: SCCCCCCNC(=O)c1cc(n[nH]1)-c1ccccn1

InChI Key: InChIKey=VRGLHLDCWONREK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50143995 (CHEMBL3758261) Show SMILES SCCCCCCNC(=O)c1cc(n[nH]1)-c1ccccn1 Show InChI InChI=1S/C15H20N4OS/c20-15(17-9-4-1-2-6-10-21)14-11-13(18-19-14)12-7-3-5-8-16-12/h3,5,7-8,11,21H,1-2,4,6,9-10H2,(H,17,20)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...				Eur J Med Chem 109: 350-9 (2016) BindingDB Entry DOI: 10.7270/Q20C4XM5
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50143995 (CHEMBL3758261) Show SMILES SCCCCCCNC(=O)c1cc(n[nH]1)-c1ccccn1 Show InChI InChI=1S/C15H20N4OS/c20-15(17-9-4-1-2-6-10-21)14-11-13(18-19-14)12-7-3-5-8-16-12/h3,5,7-8,11,21H,1-2,4,6,9-10H2,(H,17,20)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...				Eur J Med Chem 109: 350-9 (2016) BindingDB Entry DOI: 10.7270/Q20C4XM5
					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50143995 (CHEMBL3758261) Show SMILES SCCCCCCNC(=O)c1cc(n[nH]1)-c1ccccn1 Show InChI InChI=1S/C15H20N4OS/c20-15(17-9-4-1-2-6-10-21)14-11-13(18-19-14)12-7-3-5-8-16-12/h3,5,7-8,11,21H,1-2,4,6,9-10H2,(H,17,20)(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition meas...				Eur J Med Chem 109: 350-9 (2016) BindingDB Entry DOI: 10.7270/Q20C4XM5
					More data for this Ligand-Target Pair