BDBM50144129 CHEMBL64947::[4-(5-Chloro-1H-indole-2-carbonyl)-piperazin-1-yl]-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)-phenyl]-methanone

SMILES: CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=YKGPYLQOBGTYSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144129 (CHEMBL64947 | [4-(5-Chloro-1H-indole-2-carbonyl)-p...) Show SMILES CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1cc2cc(Cl)ccc2[nH]1 |c:4| Show InChI InChI=1S/C24H24ClN5O2/c1-28-9-8-26-22(28)16-2-4-17(5-3-16)23(31)29-10-12-30(13-11-29)24(32)21-15-18-14-19(25)6-7-20(18)27-21/h2-7,14-15,27H,8-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair