BDBM50145022 1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-propyl]-piperazine::1-cyclohexyl-4-(3-(5-methoxynaphthalen-1-yl)propyl)piperazine::CHEMBL535856::CHEMBL75286::PB-183

SMILES: COc1cccc2c(CCCN3CCN(CC3)C3CCCCC3)cccc12

InChI Key: InChIKey=OAXSBEWCGPXYFN-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50145022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50145022 (1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...) Show SMILES COc1cccc2c(CCCN3CCN(CC3)C3CCCCC3)cccc12 Show InChI InChI=1S/C24H34N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h5-6,8,12-14,21H,2-4,7,9-11,15-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.				J Med Chem 47: 2308-17 (2004) Article DOI: 10.1021/jm031026e BindingDB Entry DOI: 10.7270/Q2DN44HS
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50145022 (1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...) Show SMILES COc1cccc2c(CCCN3CCN(CC3)C3CCCCC3)cccc12 Show InChI InChI=1S/C24H34N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h5-6,8,12-14,21H,2-4,7,9-11,15-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membrane				J Med Chem 50: 4648-55 (2007) Article DOI: 10.1021/jm070373b BindingDB Entry DOI: 10.7270/Q2SQ917Z
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (Cavia porcellus)	BDBM50145022 (1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...) Show SMILES COc1cccc2c(CCCN3CCN(CC3)C3CCCCC3)cccc12 Show InChI InChI=1S/C24H34N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h5-6,8,12-14,21H,2-4,7,9-11,15-19H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membrane				J Med Chem 50: 4648-55 (2007) Article DOI: 10.1021/jm070373b BindingDB Entry DOI: 10.7270/Q2SQ917Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse))	BDBM50145022 (1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...) Show SMILES COc1cccc2c(CCCN3CCN(CC3)C3CCCCC3)cccc12 Show InChI InChI=1S/C24H34N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h5-6,8,12-14,21H,2-4,7,9-11,15-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from mouse sigma 1 receptor in TRAMP cell membrane				Bioorg Med Chem Lett 18: 1990-3 (2008) Article DOI: 10.1016/j.bmcl.2008.01.109 BindingDB Entry DOI: 10.7270/Q2CR5V70
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50145022 (1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...) Show SMILES COc1cccc2c(CCCN3CCN(CC3)C3CCCCC3)cccc12 Show InChI InChI=1S/C24H34N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h5-6,8,12-14,21H,2-4,7,9-11,15-19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding affinity at serotonin 5-hydroxytryptamine 3 receptor in rat cortex by [3H]-granisetron displacement.				J Med Chem 47: 2308-17 (2004) Article DOI: 10.1021/jm031026e BindingDB Entry DOI: 10.7270/Q2DN44HS
					More data for this Ligand-Target Pair