BDBM50145024 5-[3-(4-Cyclohexyl-piperazin-1-yl)-propyl]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL73964
SMILES: Oc1ccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc2c1
InChI Key: InChIKey=QGKGZEGBAYIKEG-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50145024 (5-[3-(4-Cyclohexyl-piperazin-1-yl)-propyl]-5,6,7,8...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Bari Curated by ChEMBL | Assay Description In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement. | J Med Chem 47: 2308-17 (2004) Article DOI: 10.1021/jm031026e BindingDB Entry DOI: 10.7270/Q2DN44HS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT) | BDBM50145024 (5-[3-(4-Cyclohexyl-piperazin-1-yl)-propyl]-5,6,7,8...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Bari Curated by ChEMBL | Assay Description In vitro binding affinity at serotonin 5-hydroxytryptamine 3 receptor in rat cortex by [3H]-granisetron displacement. | J Med Chem 47: 2308-17 (2004) Article DOI: 10.1021/jm031026e BindingDB Entry DOI: 10.7270/Q2DN44HS | |||||||||||
More data for this Ligand-Target Pair |