BDBM50145050 1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-phenyl-propenone::1-(6-hydroxy-4,7-dimethoxybenzofuran-5-yl)-3-phenylprop-2-en-1-one::CHEMBL310916

SMILES: COc1c(O)c(C(=O)\C=C\c2ccccc2)c(OC)c2ccoc12

InChI Key: InChIKey=YUHVWUKXIRHANR-CMDGGOBGSA-N

Data: 1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50145050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50145050 (1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-phen...) Show SMILES COc1c(O)c(C(=O)\C=C\c2ccccc2)c(OC)c2ccoc12 Show InChI InChI=1S/C19H16O5/c1-22-17-13-10-11-24-18(13)19(23-2)16(21)15(17)14(20)9-8-12-6-4-3-5-7-12/h3-11,21H,1-2H3/b9-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
The Walter and Eliza Hall Institute of Medical Research Curated by ChEMBL					Assay Description Inhibition in Kv1.3 expressed in human L929 by patch clamp method				Bioorg Med Chem Lett 18: 2055-61 (2008) Article DOI: 10.1016/j.bmcl.2008.01.099 BindingDB Entry DOI: 10.7270/Q2ZG6T27
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily A member 3 (Homo sapiens (Human))	BDBM50145050 (1-(6-Hydroxy-4,7-dimethoxy-benzofuran-5-yl)-3-phen...) Show SMILES COc1c(O)c(C(=O)\C=C\c2ccccc2)c(OC)c2ccoc12 Show InChI InChI=1S/C19H16O5/c1-22-17-13-10-11-24-18(13)19(23-2)16(21)15(17)14(20)9-8-12-6-4-3-5-7-12/h3-11,21H,1-2H3/b9-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Dissociation constant for the blockage of voltage-gated potassium channel subunit Kv1.3 in human lymphocytes				J Med Chem 47: 2326-36 (2004) Article DOI: 10.1021/jm030523s BindingDB Entry DOI: 10.7270/Q28W3CRM
					More data for this Ligand-Target Pair