BDBM50145998 (1S,5S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionyl]-2-aza-bicyclo[3.1.0]hexane-3-carbonitrile; TFA::CHEMBL89465

SMILES: N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1[C@H]2C[C@H]2CC1C#N

InChI Key: InChIKey=JCRCTLVTPHWAJU-KSOLFMMOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50145998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase IV (Sus scrofa (pig))	BDBM50145998 ((1S,5S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionyl...) Show SMILES N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1[C@H]2C[C@H]2CC1C#N Show InChI InChI=1S/C17H18N4O/c18-8-12-5-10-7-16(10)21(12)17(22)14(19)6-11-9-20-15-4-2-1-3-13(11)15/h1-4,9-10,12,14,16,20H,5-7,19H2/t10-,12?,14+,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of porcine Dipeptidylpeptidase IV.				J Med Chem 47: 2587-98 (2004) Article DOI: 10.1021/jm049924d BindingDB Entry DOI: 10.7270/Q2FT8MSQ
					More data for this Ligand-Target Pair