BDBM50147423 CHEMBL432422::N-(7-Benzo[1,3]dioxol-5-yl-4-chloro-isoquinolin-1-yl)-guanidine

SMILES: [#7]\[#6](-[#7])=[#7]\c1ncc(Cl)c2ccc(cc12)-c1ccc2-[#8]-[#6]-[#8]-c2c1

InChI Key: InChIKey=OHZKUBPASKSZOQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50147423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50147423 (CHEMBL432422 | N-(7-Benzo[1,3]dioxol-5-yl-4-chloro...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1ncc(Cl)c2ccc(cc12)-c1ccc2-[#8]-[#6]-[#8]-c2c1 Show InChI InChI=1S/C17H13ClN4O2/c18-13-7-21-16(22-17(19)20)12-5-9(1-3-11(12)13)10-2-4-14-15(6-10)24-8-23-14/h1-7H,8H2,(H4,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human urokinase-type plasminogen activator was evaluated using S-2444 as substrate				Bioorg Med Chem Lett 14: 3227-30 (2004) Article DOI: 10.1016/j.bmcl.2004.03.094 BindingDB Entry DOI: 10.7270/Q2125S3C
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50147423 (CHEMBL432422 | N-(7-Benzo[1,3]dioxol-5-yl-4-chloro...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1ncc(Cl)c2ccc(cc12)-c1ccc2-[#8]-[#6]-[#8]-c2c1 Show InChI InChI=1S/C17H13ClN4O2/c18-13-7-21-16(22-17(19)20)12-5-9(1-3-11(12)13)10-2-4-14-15(6-10)24-8-23-14/h1-7H,8H2,(H4,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human plasmin activity with chromozym-PL as substrate				Bioorg Med Chem Lett 14: 3227-30 (2004) Article DOI: 10.1016/j.bmcl.2004.03.094 BindingDB Entry DOI: 10.7270/Q2125S3C
					More data for this Ligand-Target Pair