BDBM50148281 CHEMBL3770847

SMILES: CC(=O)c1cc(-c2ccccc2S(C)(=O)=O)c2ccccn12

InChI Key: InChIKey=RAUURLIZMTUFSY-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain adjacent to zinc finger domain protein 2A (Homo sapiens (Human))	BDBM50148281 (CHEMBL3770847) Show SMILES CC(=O)c1cc(-c2ccccc2S(C)(=O)=O)c2ccccn12 Show InChI InChI=1S/C17H15NO3S/c1-12(19)16-11-14(15-8-5-6-10-18(15)16)13-7-3-4-9-17(13)22(2,20)21/h3-11H,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant His6-TEV fused human BAZ2A expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...				J Med Chem 59: 1410-24 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J09
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50148281 (CHEMBL3770847) Show SMILES CC(=O)c1cc(-c2ccccc2S(C)(=O)=O)c2ccccn12 Show InChI InChI=1S/C17H15NO3S/c1-12(19)16-11-14(15-8-5-6-10-18(15)16)13-7-3-4-9-17(13)22(2,20)21/h3-11H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of BRD4 bromodomain 1 (unknown origin) incubated for 30 mins in presence of biotinylated peptide by alpha screen assay				J Med Chem 59: 1410-24 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J09
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Homo sapiens (Human))	BDBM50148281 (CHEMBL3770847) Show SMILES CC(=O)c1cc(-c2ccccc2S(C)(=O)=O)c2ccccn12 Show InChI InChI=1S/C17H15NO3S/c1-12(19)16-11-14(15-8-5-6-10-18(15)16)13-7-3-4-9-17(13)22(2,20)21/h3-11H,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of BRD9 (unknown origin) incubated for 30 mins in presence of biotinylated peptide by alpha screen assay				J Med Chem 59: 1410-24 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J09
					More data for this Ligand-Target Pair
Bromodomain adjacent to zinc finger domain protein 2B (Homo sapiens (Human))	BDBM50148281 (CHEMBL3770847) Show SMILES CC(=O)c1cc(-c2ccccc2S(C)(=O)=O)c2ccccn12 Show InChI InChI=1S/C17H15NO3S/c1-12(19)16-11-14(15-8-5-6-10-18(15)16)13-7-3-4-9-17(13)22(2,20)21/h3-11H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...				J Med Chem 59: 1410-24 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J09
					More data for this Ligand-Target Pair