BDBM50148334 CHEMBL3770214

SMILES: COc1ccn2c(cc(-c3ccccc3S(C)(=O)=O)c2c1)C(C)=O

InChI Key: InChIKey=XEDBHRINPFDNQZ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain adjacent to zinc finger domain protein 2A (Homo sapiens (Human))	BDBM50148334 (CHEMBL3770214) Show SMILES COc1ccn2c(cc(-c3ccccc3S(C)(=O)=O)c2c1)C(C)=O Show InChI InChI=1S/C18H17NO4S/c1-12(20)16-11-15(17-10-13(23-2)8-9-19(16)17)14-6-4-5-7-18(14)24(3,21)22/h4-11H,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant His6-TEV fused human BAZ2A expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...				J Med Chem 59: 1410-24 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J09
					More data for this Ligand-Target Pair
Bromodomain-containing protein 9 (Homo sapiens (Human))	BDBM50148334 (CHEMBL3770214) Show SMILES COc1ccn2c(cc(-c3ccccc3S(C)(=O)=O)c2c1)C(C)=O Show InChI InChI=1S/C18H17NO4S/c1-12(20)16-11-15(17-10-13(23-2)8-9-19(16)17)14-6-4-5-7-18(14)24(3,21)22/h4-11H,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of BRD9 (unknown origin) incubated for 30 mins in presence of biotinylated peptide by alpha screen assay				J Med Chem 59: 1410-24 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J09
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50148334 (CHEMBL3770214) Show SMILES COc1ccn2c(cc(-c3ccccc3S(C)(=O)=O)c2c1)C(C)=O Show InChI InChI=1S/C18H17NO4S/c1-12(20)16-11-15(17-10-13(23-2)8-9-19(16)17)14-6-4-5-7-18(14)24(3,21)22/h4-11H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of BRD4 bromodomain 1 (unknown origin) incubated for 30 mins in presence of biotinylated peptide by alpha screen assay				J Med Chem 59: 1410-24 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J09
					More data for this Ligand-Target Pair
Bromodomain adjacent to zinc finger domain protein 2B (Homo sapiens (Human))	BDBM50148334 (CHEMBL3770214) Show SMILES COc1ccn2c(cc(-c3ccccc3S(C)(=O)=O)c2c1)C(C)=O Show InChI InChI=1S/C18H17NO4S/c1-12(20)16-11-15(17-10-13(23-2)8-9-19(16)17)14-6-4-5-7-18(14)24(3,21)22/h4-11H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant His6-TEV fused human BAZ2B expressed in Escherichia coli incubated for 30 mins in presence of biotinylated peptide by alpha...				J Med Chem 59: 1410-24 (2016) BindingDB Entry DOI: 10.7270/Q2PK0J09
					More data for this Ligand-Target Pair