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SMILES: CN(C)COc1ccc(cc1)-c1cc(on1)-c1ccc(F)cc1

InChI Key: InChIKey=OCSBAOOQUDGZGV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150559 (CHEMBL182361 | {4-[5-(4-Fluoro-phenyl)-isoxazol-3-...) Show SMILES CN(C)COc1ccc(cc1)-c1cc(on1)-c1ccc(F)cc1 Show InChI InChI=1S/C18H17FN2O2/c1-21(2)12-22-16-9-5-13(6-10-16)17-11-18(23-20-17)14-3-7-15(19)8-4-14/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150559 (CHEMBL182361 | {4-[5-(4-Fluoro-phenyl)-isoxazol-3-...) Show SMILES CN(C)COc1ccc(cc1)-c1cc(on1)-c1ccc(F)cc1 Show InChI InChI=1S/C18H17FN2O2/c1-21(2)12-22-16-9-5-13(6-10-16)17-11-18(23-20-17)14-3-7-15(19)8-4-14/h3-11H,12H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of interleukin-8 induced elastase release from human neutrophils				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair