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SMILES: Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(Cc1cnc[nH]1)C(O)=O

InChI Key: InChIKey=TYUGMMOCSRYPGE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50150810   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mu-type opioid receptor


(GUINEA PIG)		BDBM50150810
PNG
((R)-2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Show SMILES Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C27H31N5O5/c1-15-7-20(33)8-16(2)21(15)11-22(28)26(35)32-13-18-6-4-3-5-17(18)9-24(32)25(34)31-23(27(36)37)10-19-12-29-14-30-19/h3-8,12,14,22-24,33H,9-11,13,28H2,1-2H3,(H,29,30)(H,31,34)(H,36,37)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Cagliary

Curated by ChEMBL


Assay Description
Inhibition of Opioid receptor mu 1 in guinea pig ileum assay

J Med Chem 47: 4066-71 (2004)


Article DOI: 10.1021/jm040033f
BindingDB Entry DOI: 10.7270/Q2P55N09
More data for this
Ligand-Target Pair