BDBM50151197 2-Furan-2-yl-5-(4-phenyl-piperazin-1-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ylamine::CHEMBL185888

SMILES: Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN(CC1)c1ccccc1

InChI Key: InChIKey=NDOGKSVSDODKPR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50151197 (2-Furan-2-yl-5-(4-phenyl-piperazin-1-yl)-[1,2,4]tr...) Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C18H18N8O/c19-16-21-17(22-18-20-15(23-26(16)18)14-7-4-12-27-14)25-10-8-24(9-11-25)13-5-2-1-3-6-13/h1-7,12H,8-11H2,(H2,19,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-ZM-241,385 binidng to rat brain adenosine A2a receptor				J Med Chem 47: 4291-9 (2004) Article DOI: 10.1021/jm0498405 BindingDB Entry DOI: 10.7270/Q2805235
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50151197 (2-Furan-2-yl-5-(4-phenyl-piperazin-1-yl)-[1,2,4]tr...) Show SMILES Nc1nc(nc2nc(nn12)-c1ccco1)N1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C18H18N8O/c19-16-21-17(22-18-20-15(23-26(16)18)14-7-4-12-27-14)25-10-8-24(9-11-25)13-5-2-1-3-6-13/h1-7,12H,8-11H2,(H2,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Biogen Idec, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-DPCPX binding to rat cerebral cortex adenosine A1 receptor				J Med Chem 47: 4291-9 (2004) Article DOI: 10.1021/jm0498405 BindingDB Entry DOI: 10.7270/Q2805235
					More data for this Ligand-Target Pair