BDBM50151520 3-{4-(3-chlorophenyl)-5-[4-cyanophenyl(1-methyl-1H-5-imidazolyl)methoxymethyl]-2-oxo-1,2-dihydro-1-pyridinylmethyl}benzonitrile::CHEMBL365269

SMILES: Cn1cncc1C(OCc1cn(Cc2cccc(c2)C#N)c(=O)cc1-c1cccc(Cl)c1)c1ccc(cc1)C#N

InChI Key: InChIKey=XLADCPZMAAXJBZ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151520   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Mus musculus)	BDBM50151520 (3-{4-(3-chlorophenyl)-5-[4-cyanophenyl(1-methyl-1H...) Show SMILES Cn1cncc1C(OCc1cn(Cc2cccc(c2)C#N)c(=O)cc1-c1cccc(Cl)c1)c1ccc(cc1)C#N Show InChI InChI=1S/C32H24ClN5O2/c1-37-21-36-17-30(37)32(25-10-8-22(15-34)9-11-25)40-20-27-19-38(18-24-5-2-4-23(12-24)16-35)31(39)14-29(27)26-6-3-7-28(33)13-26/h2-14,17,19,21,32H,18,20H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Factor Xa				Bioorg Med Chem Lett 14: 4603-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.004 BindingDB Entry DOI: 10.7270/Q27080WG
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50151520 (3-{4-(3-chlorophenyl)-5-[4-cyanophenyl(1-methyl-1H...) Show SMILES Cn1cncc1C(OCc1cn(Cc2cccc(c2)C#N)c(=O)cc1-c1cccc(Cl)c1)c1ccc(cc1)C#N Show InChI InChI=1S/C32H24ClN5O2/c1-37-21-36-17-30(37)32(25-10-8-22(15-34)9-11-25)40-20-27-19-38(18-24-5-2-4-23(12-24)16-35)31(39)14-29(27)26-6-3-7-28(33)13-26/h2-14,17,19,21,32H,18,20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Transcriptional repression in HepG2 cells expressing human glucocorticoid receptor				Bioorg Med Chem Lett 14: 4603-6 (2004) Article DOI: 10.1016/j.bmcl.2004.07.004 BindingDB Entry DOI: 10.7270/Q27080WG
					More data for this Ligand-Target Pair