null

SMILES: CS(=O)(=O)c1ccc2c(Sc3ccccc3Cl)c([nH]c2c1)C#N

InChI Key: InChIKey=PHIZQTIQMIXTJV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50151768 (3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES CS(=O)(=O)c1ccc2c(Sc3ccccc3Cl)c([nH]c2c1)C#N Show InChI InChI=1S/C16H11ClN2O2S2/c1-23(20,21)10-6-7-11-13(8-10)19-14(9-18)16(11)22-15-5-3-2-4-12(15)17/h2-8,19H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 1 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151768 (3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES CS(=O)(=O)c1ccc2c(Sc3ccccc3Cl)c([nH]c2c1)C#N Show InChI InChI=1S/C16H11ClN2O2S2/c1-23(20,21)10-6-7-11-13(8-10)19-14(9-18)16(11)22-15-5-3-2-4-12(15)17/h2-8,19H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151768 (3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES CS(=O)(=O)c1ccc2c(Sc3ccccc3Cl)c([nH]c2c1)C#N Show InChI InChI=1S/C16H11ClN2O2S2/c1-23(20,21)10-6-7-11-13(8-10)19-14(9-18)16(11)22-15-5-3-2-4-12(15)17/h2-8,19H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
					More data for this Ligand-Target Pair