Found 4 hits for monomerid = 50152637 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50152637
((4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-th...)Show SMILES Cc1ccc(cc1)C1=N[C@@H](S)[C@@H](O1)C=C |t:8| Show InChI InChI=1S/C12H13NOS/c1-3-10-12(15)13-11(14-10)9-6-4-8(2)5-7-9/h3-7,10,12,15H,1H2,2H3/t10-,12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against matrix metalloprotease-2 |
Bioorg Med Chem Lett 14: 4935-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.023
BindingDB Entry DOI: 10.7270/Q2PV6JT3 |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50152637
((4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-th...)Show SMILES Cc1ccc(cc1)C1=N[C@@H](S)[C@@H](O1)C=C |t:8| Show InChI InChI=1S/C12H13NOS/c1-3-10-12(15)13-11(14-10)9-6-4-8(2)5-7-9/h3-7,10,12,15H,1H2,2H3/t10-,12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against matrix metalloprotease-9 |
Bioorg Med Chem Lett 14: 4935-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.023
BindingDB Entry DOI: 10.7270/Q2PV6JT3 |
More data for this
Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50152637
((4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-th...)Show SMILES Cc1ccc(cc1)C1=N[C@@H](S)[C@@H](O1)C=C |t:8| Show InChI InChI=1S/C12H13NOS/c1-3-10-12(15)13-11(14-10)9-6-4-8(2)5-7-9/h3-7,10,12,15H,1H2,2H3/t10-,12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against matrix metalloprotease-1 |
Bioorg Med Chem Lett 14: 4935-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.023
BindingDB Entry DOI: 10.7270/Q2PV6JT3 |
More data for this
Ligand-Target Pair | |
Macrophage metalloelastase
(Homo sapiens (Human)) | BDBM50152637
((4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-th...)Show SMILES Cc1ccc(cc1)C1=N[C@@H](S)[C@@H](O1)C=C |t:8| Show InChI InChI=1S/C12H13NOS/c1-3-10-12(15)13-11(14-10)9-6-4-8(2)5-7-9/h3-7,10,12,15H,1H2,2H3/t10-,12-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
North Dakota State University
Curated by ChEMBL
| Assay Description
Inhibitory activity against matrix metalloprotease-12 |
Bioorg Med Chem Lett 14: 4935-9 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.023
BindingDB Entry DOI: 10.7270/Q2PV6JT3 |
More data for this
Ligand-Target Pair | |
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