BDBM50153930 1-(3,3-Diphenyl-propyl)-4-(4-nitro-benzyl)-[1,4]diazepane::CHEMBL184688

SMILES: [O-][N+](=O)c1ccc(CN2CCCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1

InChI Key: InChIKey=VHFIEAAZWKLLSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50153930 (1-(3,3-Diphenyl-propyl)-4-(4-nitro-benzyl)-[1,4]di...) Show SMILES [O-][N+](=O)c1ccc(CN2CCCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1 Show InChI InChI=1S/C27H31N3O2/c31-30(32)26-14-12-23(13-15-26)22-29-18-7-17-28(20-21-29)19-16-27(24-8-3-1-4-9-24)25-10-5-2-6-11-25/h1-6,8-15,27H,7,16-22H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Bio-medical Research Curated by ChEMBL					Assay Description Concentration required to inhibit [125I]-MCP-1 (Monocyte Chemoattractant Protein-1) binding to THP-1 cell				Bioorg Med Chem Lett 14: 5407-11 (2004) Article DOI: 10.1016/j.bmcl.2004.08.008 BindingDB Entry DOI: 10.7270/Q2125S4T
					More data for this Ligand-Target Pair