BDBM50153938 CHEMBL181432::N-{[1-(4-Chloro-benzyl)-piperidin-3-ylcarbamoyl]-methyl}-3-trifluoromethyl-benzamide

SMILES: FC(F)(F)c1cccc(c1)C(=O)NCC(=O)NC1CCCN(Cc2ccc(Cl)cc2)C1

InChI Key: InChIKey=WUTHMLMEUBCLDN-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50153938 (CHEMBL181432 | N-{[1-(4-Chloro-benzyl)-piperidin-3...) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCC(=O)NC1CCCN(Cc2ccc(Cl)cc2)C1 Show InChI InChI=1S/C22H23ClF3N3O2/c23-18-8-6-15(7-9-18)13-29-10-2-5-19(14-29)28-20(30)12-27-21(31)16-3-1-4-17(11-16)22(24,25)26/h1,3-4,6-9,11,19H,2,5,10,12-14H2,(H,27,31)(H,28,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	610	n/a	n/a	n/a	n/a
Deltagen Research Laboratories Curated by ChEMBL					Assay Description Inhibition of MCP-1 induced chemotaxis in THP-1 cells				Bioorg Med Chem Lett 14: 5413-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.009 BindingDB Entry DOI: 10.7270/Q2W958PZ
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50153938 (CHEMBL181432 | N-{[1-(4-Chloro-benzyl)-piperidin-3...) Show SMILES FC(F)(F)c1cccc(c1)C(=O)NCC(=O)NC1CCCN(Cc2ccc(Cl)cc2)C1 Show InChI InChI=1S/C22H23ClF3N3O2/c23-18-8-6-15(7-9-18)13-29-10-2-5-19(14-29)28-20(30)12-27-21(31)16-3-1-4-17(11-16)22(24,25)26/h1,3-4,6-9,11,19H,2,5,10,12-14H2,(H,27,31)(H,28,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Deltagen Research Laboratories Curated by ChEMBL					Assay Description Concentration required to inhibit [125I]-MCP-1 binding to Chemokine receptor 2B				Bioorg Med Chem Lett 14: 5413-6 (2004) Article DOI: 10.1016/j.bmcl.2004.08.009 BindingDB Entry DOI: 10.7270/Q2W958PZ
					More data for this Ligand-Target Pair