BDBM50154200 7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL187635

SMILES: CO[C@H]1Cc2ccc(O)cc2C(C)(C)[C@@H]1N

InChI Key: InChIKey=IGSNSHHFXGJMKP-NWDGAFQWSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50154200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50154200 (7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydron...) Show SMILES CO[C@H]1Cc2ccc(O)cc2C(C)(C)[C@@H]1N Show InChI InChI=1S/C13H19NO2/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to human Mu opioid receptor expressed in CHO cells				J Med Chem 47: 5069-75 (2004) Article DOI: 10.1021/jm040807s BindingDB Entry DOI: 10.7270/Q2S46SQB
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50154200 (7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydron...) Show SMILES CO[C@H]1Cc2ccc(O)cc2C(C)(C)[C@@H]1N Show InChI InChI=1S/C13H19NO2/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of [3H]U-69593 binding to human kappa opioid receptor expressed in CHO cells				J Med Chem 47: 5069-75 (2004) Article DOI: 10.1021/jm040807s BindingDB Entry DOI: 10.7270/Q2S46SQB
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50154200 (7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydron...) Show SMILES CO[C@H]1Cc2ccc(O)cc2C(C)(C)[C@@H]1N Show InChI InChI=1S/C13H19NO2/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of [3H]C1-DPDPE binding to human delta opioid receptor expressed in CHO cells				J Med Chem 47: 5069-75 (2004) Article DOI: 10.1021/jm040807s BindingDB Entry DOI: 10.7270/Q2S46SQB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50154200 (7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydron...) Show SMILES CO[C@H]1Cc2ccc(O)cc2C(C)(C)[C@@H]1N Show InChI InChI=1S/C13H19NO2/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	234	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at human cloned mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTP[gammaS] binding				Bioorg Med Chem Lett 24: 2021-32 (2014) Article DOI: 10.1016/j.bmcl.2014.03.040 BindingDB Entry DOI: 10.7270/Q2222WBX
					More data for this Ligand-Target Pair