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BDBM50154473 6-Bromo-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-methyl-1H-imidazo[1,2-a]imidazol-2-one::CHEMBL187542

SMILES: CC1(Cc2ccc(Br)cc2)C(=O)N(c2nc(Br)cn12)c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=LXBNAFUQTGPRDK-UHFFFAOYSA-N

Data: 1 Kd

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50154473   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin beta-2/Leukocyte adhesion glycoprotein LFA-1 alpha


(Homo sapiens (Human))
BDBM50154473
PNG
(6-Bromo-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl)...)
Show SMILES CC1(Cc2ccc(Br)cc2)C(=O)N(c2nc(Br)cn12)c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C19H13Br2Cl2N3O/c1-19(9-11-2-4-12(20)5-3-11)17(27)26(18-24-16(21)10-25(18)19)15-7-13(22)6-14(23)8-15/h2-8,10H,9H2,1H3
PDB

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PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/a 630n/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay


J Med Chem 47: 5356-66 (2004)


Article DOI: 10.1021/jm049657b
BindingDB Entry DOI: 10.7270/Q2B857MB
More data for this
Ligand-Target Pair