null

SMILES: CO\N=C\c1cn2CCNC(=O)c3cccc1c23

InChI Key: InChIKey=MPYDWEZEBNJFME-VIZOYTHASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154727   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50154727 (1-Oxo-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]i...) Show SMILES CO\N=C\c1cn2CCNC(=O)c3cccc1c23 Show InChI InChI=1S/C13H13N3O2/c1-18-15-7-9-8-16-6-5-14-13(17)11-4-2-3-10(9)12(11)16/h2-4,7-8H,5-6H2,1H3,(H,14,17)/b15-7+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	809	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human PARP-1				J Med Chem 54: 2529-91 (2011) Article DOI: 10.1021/jm1013693 BindingDB Entry DOI: 10.7270/Q24M95PH
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50154727 (1-Oxo-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]i...) Show SMILES CO\N=C\c1cn2CCNC(=O)c3cccc1c23 Show InChI InChI=1S/C13H13N3O2/c1-18-15-7-9-8-16-6-5-14-13(17)11-4-2-3-10(9)12(11)16/h2-4,7-8H,5-6H2,1H3,(H,14,17)/b15-7+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	809	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global R&D--La Jolla Laboratories Curated by ChEMBL					Assay Description Inhibition of human Poly (ADP-ribose) polymerase 1 enzyme				J Med Chem 47: 5467-81 (2004) Article DOI: 10.1021/jm030513r BindingDB Entry DOI: 10.7270/Q2PK0FM4
					More data for this Ligand-Target Pair