BDBM50155128 CHEMBL183203::N,N-dimethyl-2-(3-(phenylsulfonyl)-1H-indol-1-yl)ethanamine::[2-(3-Benzenesulfonyl-indol-1-yl)-ethyl]-dimethyl-amine
SMILES: CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1ccccc1
InChI Key: InChIKey=JRCURRGCAIWUMY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50155128![]() (CHEMBL183203 | N,N-dimethyl-2-(3-(phenylsulfonyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells | Bioorg Med Chem Lett 14: 5499-502 (2004) Article DOI: 10.1016/j.bmcl.2004.09.003 BindingDB Entry DOI: 10.7270/Q2SB457X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50155128![]() (CHEMBL183203 | N,N-dimethyl-2-(3-(phenylsulfonyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells | Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50155128![]() (CHEMBL183203 | N,N-dimethyl-2-(3-(phenylsulfonyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 366 | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Agonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as induction of adenylyl cyclase activity by RIA | Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS | |||||||||||
More data for this Ligand-Target Pair |