null
SMILES: CCN(CC)CCc1c(C)[nH]c(\C=C2/C(=O)NN=C2c2cnccn2)c1C
InChI Key: InChIKey=DBHHGWWEFJEXFX-WJDWOHSUSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM50155148 ((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of Chk1 | J Med Chem 52: 3159-65 (2009) Article DOI: 10.1021/jm801444x BindingDB Entry DOI: 10.7270/Q2FF3TM8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50155148 ((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol) | Bioorg Med Chem Lett 14: 5503-7 (2004) Article DOI: 10.1016/j.bmcl.2004.09.007 BindingDB Entry DOI: 10.7270/Q2NK3DJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50155148 ((Z)-4-((4-(2-(diethylamino)ethyl)-3,5-dimethyl-1H-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Bioresearch Center Curated by ChEMBL | Assay Description Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol) | Bioorg Med Chem Lett 14: 5503-7 (2004) Article DOI: 10.1016/j.bmcl.2004.09.007 BindingDB Entry DOI: 10.7270/Q2NK3DJN | |||||||||||
More data for this Ligand-Target Pair |