BDBM50155468 2-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-6-methoxy-3,4-dihydro-2H-naphthalen-1-one::2-[1-(2-bromophenyl)methylidene]-6-methoxy-3,4-dihydro-2H-naphthalen-1-one::CHEMBL363682

SMILES: COc1ccc2C(=O)\C(CCc2c1)=C\c1ccccc1Br

InChI Key: InChIKey=ZHOQTMYSBFYMPC-GXDHUFHOSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 24A1 (Rattus norvegicus)	BDBM50155468 (2-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-6-methoxy-...) Show SMILES COc1ccc2C(=O)\C(CCc2c1)=C\c1ccccc1Br Show InChI InChI=1S/C18H15BrO2/c1-21-15-8-9-16-12(11-15)6-7-14(18(16)20)10-13-4-2-3-5-17(13)19/h2-5,8-11H,6-7H2,1H3/b14-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibitory activity against 25-hydroxyvitamin D3 24-hydroxylase of rat kidney mitochondria				Bioorg Med Chem Lett 14: 5651-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.040 BindingDB Entry DOI: 10.7270/Q2GX4B2T
					More data for this Ligand-Target Pair
Cytochrome P450 24A1 (Homo sapiens (Human))	BDBM50155468 (2-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-6-methoxy-...) Show SMILES COc1ccc2C(=O)\C(CCc2c1)=C\c1ccccc1Br Show InChI InChI=1S/C18H15BrO2/c1-21-15-8-9-16-12(11-15)6-7-14(18(16)20)10-13-4-2-3-5-17(13)19/h2-5,8-11H,6-7H2,1H3/b14-10+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of CYP24A1 expressed in CHO cells				Eur J Med Chem 45: 4427-34 (2010) Article DOI: 10.1016/j.ejmech.2010.07.001 BindingDB Entry DOI: 10.7270/Q2ZW1M4W
					More data for this Ligand-Target Pair
Sterol 26-hydroxylase, mitochondrial (Homo sapiens (Human))	BDBM50155468 (2-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-6-methoxy-...) Show SMILES COc1ccc2C(=O)\C(CCc2c1)=C\c1ccccc1Br Show InChI InChI=1S/C18H15BrO2/c1-21-15-8-9-16-12(11-15)6-7-14(18(16)20)10-13-4-2-3-5-17(13)19/h2-5,8-11H,6-7H2,1H3/b14-10+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of CYP27A1 expressed in CHO cells				Eur J Med Chem 45: 4427-34 (2010) Article DOI: 10.1016/j.ejmech.2010.07.001 BindingDB Entry DOI: 10.7270/Q2ZW1M4W
					More data for this Ligand-Target Pair