BDBM50155820 2-Cyano-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-3-[4-(5-fluoro-2-trifluoromethyl-benzyloxy)-3-methoxy-phenyl]-acrylamide::CHEMBL365887

SMILES: CCc1nnc(NC(=O)C(=C\c2ccc(OCc3cc(F)ccc3C(F)(F)F)c(OC)c2)\C#N)s1

InChI Key: InChIKey=WOVGPIQBIVGZJW-RIYZIHGNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen-related receptor alpha (Homo sapiens (Human))	BDBM50155820 (2-Cyano-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-3-[4-(5...) Show SMILES CCc1nnc(NC(=O)C(=C\c2ccc(OCc3cc(F)ccc3C(F)(F)F)c(OC)c2)\C#N)s1 Show InChI InChI=1S/C23H18F4N4O3S/c1-3-20-30-31-22(35-20)29-21(32)14(11-28)8-13-4-7-18(19(9-13)33-2)34-12-15-10-16(24)5-6-17(15)23(25,26)27/h4-10H,3,12H2,1-2H3,(H,29,31,32)/b14-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
X-Ceptor Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of estrogen-related receptor alpha Gal4 activity				J Med Chem 47: 5593-6 (2004) Article DOI: 10.1021/jm049334f BindingDB Entry DOI: 10.7270/Q2959H16
					More data for this Ligand-Target Pair
Estrogen-related receptor alpha (Homo sapiens (Human))	BDBM50155820 (2-Cyano-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-3-[4-(5...) Show SMILES CCc1nnc(NC(=O)C(=C\c2ccc(OCc3cc(F)ccc3C(F)(F)F)c(OC)c2)\C#N)s1 Show InChI InChI=1S/C23H18F4N4O3S/c1-3-20-30-31-22(35-20)29-21(32)14(11-28)8-13-4-7-18(19(9-13)33-2)34-12-15-10-16(24)5-6-17(15)23(25,26)27/h4-10H,3,12H2,1-2H3,(H,29,31,32)/b14-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
X-Ceptor Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of estrogen-related receptor alpha Gal4 activity				J Med Chem 47: 5593-6 (2004) Article DOI: 10.1021/jm049334f BindingDB Entry DOI: 10.7270/Q2959H16
					More data for this Ligand-Target Pair