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SMILES: COc1ccc(cc1N)-c1nnc2n(C)c(=O)c3ccccc3n12

InChI Key: InChIKey=HRJFKYULANSZOV-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156447   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Similar to alpha-tubulin isoform 1


(Bos taurus)		BDBM50156447
PNG
(CHEMBL3792513)
Show SMILES COc1ccc(cc1N)-c1nnc2n(C)c(=O)c3ccccc3n12
Show InChI InChI=1S/C17H15N5O2/c1-21-16(23)11-5-3-4-6-13(11)22-15(19-20-17(21)22)10-7-8-14(24-2)12(18)9-10/h3-9H,18H2,1-2H3
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ de Lille

Curated by ChEMBL


Assay Description
Inhibition of bovine tubulin polymerization after 1 hr by fluorescence spectrometry

Eur J Med Chem 115: 393-405 (2016)


Article DOI: 10.1016/j.ejmech.2016.03.056
BindingDB Entry DOI: 10.7270/Q2RN39RQ
More data for this
Ligand-Target Pair