BDBM50157497 4-[6-hydroxy-1-(2,2,2-trifluoroethyl)-1H-indazol-3-yl]benzene-1,3-dio::CHEMBL225404

SMILES: Oc1ccc(-c2nn(CC(F)(F)F)c3cc(O)ccc23)c(O)c1

InChI Key: InChIKey=YUMVZGGRPJTXIJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50157497 (4-[6-hydroxy-1-(2,2,2-trifluoroethyl)-1H-indazol-3...) Show SMILES Oc1ccc(-c2nn(CC(F)(F)F)c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C15H11F3N2O3/c16-15(17,18)7-20-12-5-8(21)1-3-10(12)14(19-20)11-4-2-9(22)6-13(11)23/h1-6,21-23H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.79E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as stimulation of creatine kinase activity				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157497 (4-[6-hydroxy-1-(2,2,2-trifluoroethyl)-1H-indazol-3...) Show SMILES Oc1ccc(-c2nn(CC(F)(F)F)c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C15H11F3N2O3/c16-15(17,18)7-20-12-5-8(21)1-3-10(12)14(19-20)11-4-2-9(22)6-13(11)23/h1-6,21-23H,7H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair