BDBM50157551 6-(7,8-dimethoxy-4-oxo-4H-chromen-2-yl)-3-hydroxyquinoxalin-2(1H)-one::CHEMBL436311

SMILES: COc1ccc2c(oc(cc2=O)-c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1OC

InChI Key: InChIKey=XRYONRLVPGGMNF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50157551 (6-(7,8-dimethoxy-4-oxo-4H-chromen-2-yl)-3-hydroxyq...) Show SMILES COc1ccc2c(oc(cc2=O)-c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1OC Show InChI InChI=1S/C19H14N2O6/c1-25-14-6-4-10-13(22)8-15(27-16(10)17(14)26-2)9-3-5-11-12(7-9)21-19(24)18(23)20-11/h3-8H,1-2H3,(H,20,23)(H,21,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BU-Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase from HEK293 cell extracts by Flash-Plate assay				J Med Chem 47: 6466-75 (2004) Article DOI: 10.1021/jm040810b BindingDB Entry DOI: 10.7270/Q2P55N1R
					More data for this Ligand-Target Pair