BDBM50158254 5-Chloro-1H-indole-2-carboxylic acid [(cyanomethyl-cyclopentyl-carbamoyl)-methyl]-amide::CHEMBL433766

SMILES: Clc1ccc2[nH]c(cc2c1)C(=O)NCC(=O)N(CC#N)C1CCCC1

InChI Key: InChIKey=COLMWAWAPQIMQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50158254 (5-Chloro-1H-indole-2-carboxylic acid [(cyanomethyl...) Show SMILES Clc1ccc2[nH]c(cc2c1)C(=O)NCC(=O)N(CC#N)C1CCCC1 Show InChI InChI=1S/C18H19ClN4O2/c19-13-5-6-15-12(9-13)10-16(22-15)18(25)21-11-17(24)23(8-7-20)14-3-1-2-4-14/h5-6,9-10,14,22H,1-4,8,11H2,(H,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against glycogen phosphorylase				Bioorg Med Chem Lett 15: 459-65 (2004) Article DOI: 10.1016/j.bmcl.2004.10.048 BindingDB Entry DOI: 10.7270/Q26W99K6
					More data for this Ligand-Target Pair