null

SMILES: FC(F)(F)S(=O)(=O)Nc1ccncc1Sc1ccccc1

InChI Key: InChIKey=ALOKHRRVYXMQQV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50158437 (CHEMBL224612 | N-(3-phenylsulfanyl-4-pyridinyl)tri...) Show SMILES FC(F)(F)S(=O)(=O)Nc1ccncc1Sc1ccccc1 Show InChI InChI=1S/C12H9F3N2O2S2/c13-12(14,15)21(18,19)17-10-6-7-16-8-11(10)20-9-4-2-1-3-5-9/h1-8H,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Université de Liège Curated by ChEMBL					Assay Description Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 production				J Med Chem 47: 6749-59 (2004) Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50158437 (CHEMBL224612 | N-(3-phenylsulfanyl-4-pyridinyl)tri...) Show SMILES FC(F)(F)S(=O)(=O)Nc1ccncc1Sc1ccccc1 Show InChI InChI=1S/C12H9F3N2O2S2/c13-12(14,15)21(18,19)17-10-6-7-16-8-11(10)20-9-4-2-1-3-5-9/h1-8H,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Université de Liège Curated by ChEMBL					Assay Description Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...				J Med Chem 47: 6749-59 (2004) Article DOI: 10.1021/jm049480l BindingDB Entry DOI: 10.7270/Q2FF3RVK
					More data for this Ligand-Target Pair