BDBM50158748 CHEMBL368194::N-(4-Hydroxy-phenyl)-3-{5-[1-(2-methoxy-phenyl)-meth-(E)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-propionamide

SMILES: COc1ccccc1\C=C1\SC(=S)N(CCC(=O)Nc2ccc(O)cc2)C1=O

InChI Key: InChIKey=UGRUUXWCKGCZIU-SFQUDFHCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158748   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158748 (CHEMBL368194 | N-(4-Hydroxy-phenyl)-3-{5-[1-(2-met...) Show SMILES COc1ccccc1\C=C1\SC(=S)N(CCC(=O)Nc2ccc(O)cc2)C1=O Show InChI InChI=1S/C20H18N2O4S2/c1-26-16-5-3-2-4-13(16)12-17-19(25)22(20(27)28-17)11-10-18(24)21-14-6-8-15(23)9-7-14/h2-9,12,23H,10-11H2,1H3,(H,21,24)/b17-12+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (3'-processing)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158748 (CHEMBL368194 | N-(4-Hydroxy-phenyl)-3-{5-[1-(2-met...) Show SMILES COc1ccccc1\C=C1\SC(=S)N(CCC(=O)Nc2ccc(O)cc2)C1=O Show InChI InChI=1S/C20H18N2O4S2/c1-26-16-5-3-2-4-13(16)12-17-19(25)22(20(27)28-17)11-10-18(24)21-14-6-8-15(23)9-7-14/h2-9,12,23H,10-11H2,1H3,(H,21,24)/b17-12+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (Strand Transfer)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair