BDBM50159123 6-Cyclohexyl-2-(4-cyclopropyl-piperazin-1-yl)-quinoline::CHEMBL362399

SMILES: C1CC1N1CCN(CC1)c1ccc2cc(ccc2n1)C1CCCCC1

InChI Key: InChIKey=QUTAEBNYXKXKBI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159123   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159123 (6-Cyclohexyl-2-(4-cyclopropyl-piperazin-1-yl)-quin...) Show SMILES C1CC1N1CCN(CC1)c1ccc2cc(ccc2n1)C1CCCCC1 Show InChI InChI=1S/C22H29N3/c1-2-4-17(5-3-1)18-6-10-21-19(16-18)7-11-22(23-21)25-14-12-24(13-15-25)20-8-9-20/h6-7,10-11,16-17,20H,1-5,8-9,12-15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair