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SMILES: Cc1cccc(n1)C#Cc1cccc(OC(=O)Cc2ccccc2)c1

InChI Key: InChIKey=RJINFAHMSRSECM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160643   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50160643
PNG
(CHEMBL182911 | Phenyl-acetic acid 3-(6-methyl-pyri...)
Show SMILES Cc1cccc(n1)C#Cc1cccc(OC(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C22H17NO2/c1-17-7-5-11-20(23-17)14-13-19-10-6-12-21(15-19)25-22(24)16-18-8-3-2-4-9-18/h2-12,15H,16H2,1H3
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Article
PubMed
n/an/a 740n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay

Bioorg Med Chem Lett 15: 945-9 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.047
BindingDB Entry DOI: 10.7270/Q2QN6681
More data for this
Ligand-Target Pair